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David Croteau Selected Research

IL13-PE38

1/2011Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study.
8/2010Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.
11/2007Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
7/2007Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions.
3/2007Induction of hyperintense signal on T2-weighted MR images correlates with infusion distribution from intracerebral convection-enhanced delivery of a tumor-targeted cytotoxin.
2/2007Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning.
4/2006Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies.
2/2005Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma.

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David Croteau Research Topics

Disease

10Neoplasms (Cancer)
01/2011 - 02/2005
8Glioma (Gliomas)
11/2007 - 02/2005
2HIV Infections (HIV Infection)
01/2018 - 03/2013
2Glioblastoma (Glioblastoma Multiforme)
01/2011 - 08/2010
2Brain Neoplasms (Brain Tumor)
11/2010 - 06/2006
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
05/2022
1Hyperkinesis
05/2022
1Hypertension (High Blood Pressure)
01/2021
1Multiple Sclerosis
01/2021
1Opportunistic Infections (Opportunistic Infection)
01/2021
1Progressive Multifocal Leukoencephalopathy
01/2021
1Wounds and Injuries (Trauma)
01/2020
1Acalculous Cholecystitis
01/2018
1Relapsing-Remitting Multiple Sclerosis
01/2018
1Critical Illness (Critically Ill)
01/2018
1Cytokine Release Syndrome
01/2018
1Acquired Immunodeficiency Syndrome (AIDS)
04/2016
1Coinfection
04/2016
1Neoplasm Metastasis (Metastasis)
11/2010
1Aphasia (Dysphasia)
11/2007
1Confusion (Bewilderment)
11/2007
1Gaucher Disease (Gaucher's Disease)
07/2007

Drug/Important Bio-Agent (IBA)

8IL13-PE38IBA
01/2011 - 02/2005
7Cytotoxins (Cytolysins)IBA
11/2007 - 02/2005
5Pharmaceutical PreparationsIBA
05/2022 - 04/2006
4Interleukin-13IBA
11/2007 - 02/2005
3ExotoxinsIBA
11/2007 - 02/2005
3Human Serum AlbuminFDA LinkGeneric
07/2007 - 02/2007
2poliferprosan 20 drug combination carmustine (Gliadel)FDA Link
01/2011 - 08/2010
2Temozolomide (Temodar)FDA LinkGeneric
11/2010 - 11/2007
1Methylphenidate (Ritalin)FDA LinkGeneric
05/2022
1Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric
05/2022
1Amphetamine (Amfetamine)FDA LinkGeneric
05/2022
1Antipsychotic Agents (Antipsychotics)IBA
05/2022
1Risperidone (Risperdal Consta)FDA LinkGeneric
05/2022
1Fingolimod Hydrochloride (FTY720)FDA Link
01/2021
1Dimethyl FumarateIBA
01/2021
1erenumabIBA
01/2021
1Eszopiclone (Lunesta)FDA Link
01/2020
1zaleplon (Sonata)FDA LinkGeneric
01/2020
1Zolpidem (Ambien)FDA LinkGeneric
01/2020
1Alemtuzumab (Campath)FDA Link
01/2018
1RNA (Ribonucleic Acid)IBA
04/2016
1Darunavir (Prezista)FDA Link
03/2013
1Carmustine (FIVB)FDA Link
08/2010
1IodineIBA
07/2007
1Pentetic Acid (DTPA)FDA LinkGeneric
07/2007
1AcidsIBA
07/2007
1Interleukin-13 Receptors (Interleukin 13 Receptor)IBA
06/2006
1CytokinesIBA
06/2006
1Pseudomonas aeruginosa Exotoxin AIBA
04/2006
1InterleukinsIBA
02/2005
1Biological ProductsIBA
02/2005
1Biomarkers (Surrogate Marker)IBA
02/2005

Therapy/Procedure

6Catheters
01/2011 - 02/2005
2Therapeutics
01/2018 - 06/2006
2Radiotherapy
11/2010 - 11/2007
1Conservative Treatment
01/2018
1Chemoradiotherapy
11/2007
1Operative Surgical Procedures
04/2006